From Orlando International Airport: Take the North Exit to West Hwy 528. Proceed West on Hwy 528 approximately 7 miles, to the I-4 exit. Take I-4 West to exit 64 (Hwy 192 West). Go West on Hwy. 192 approximately 5 miles. Turn right into Lighthouse Key Resort (just past Orange Lake Blvd.).

From Sanford Airport: Take I-4 West to exit 64 (Hwy 192 West). Go West on Hwy. 192 approximately 5 miles. Turn right into Lighthouse Key Resort (just past Orange Lake Blvd.).

From Florida Turnpike (coming from the South): Exit Turnpike at Osceola Parkway. Proceed West on Osceola Parkway to S. International Drive (approx. 9 miles) and turn left. Drive approx. 1 mile and turn right on Hwy. 192 (Irlo Bronson Memorial Hwy.) Go West on Hwy. 192 approximately 5 miles. Turn right into Lighthouse Key Resort (just past Orange Lake Blvd.).

From Florida Turnpike (coming from the North): Exit Turnpike at exit 267A (Toll 429/Western Beltway) Take Toll 429 SOUTH to exit 6 (U.S. 192/Kissimmee). Turn right onto Hwy. 192 and drive 0.6 miles. Turn right into Lighthouse Key Resort (just past Orange Lake Blvd.).

From Interstate 75: Follow Interstate 75 onto Florida Turnpike, heading east. Exit Turnpike at exit 267A (Toll 429/Western Beltway) Take Toll 429 SOUTH to exit 6 (U.S. 192/Kissimmee). Turn right onto Hwy. 192 and drive approximately 0.6 miles. Just past Orange Lake Blvd., turn right into Lighthouse Key Resort.

From Interstate 95: Take Interstate 95 onto I-4. Take I-4 West to exit 64 (Hwy 192 West). Go West on Hwy. 192 approximately 5 miles. Turn right into Lighthouse Key Resort (just past Orange Lake Blvd.).

From Miami: Take I-95 North to the Florida Turnpike. Take Florida Turnpike North. Exit onto Osceola Parkway. Proceed West on Osceola Parkway to S. International Drive (approx. 9 miles) and turn left. Drive approx. 1 mile and turn right on Hwy. 192 (Irlo Bronson Memorial Hwy.) Go West on Hwy. 192 approximately 5 miles. Turn right into Lighthouse Key Resort (just past Orange Lake Blvd.).

From Tampa: Exit I-4 at SR 429 (Exit 60). Take Toll 429 North to Exit 6 (U.S. 192/Kissimmee). Turn left onto Hwy. 192 and drive approximately 0.77 miles. Turn right into Lighthouse Key Resort (just past Orange Lake Blvd.).